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The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence Clostridioides difficile Clearance in Mice

The gut microbiota has a key role in determining susceptibility to Clostridioides difficile infections (CDIs). However, much of the mechanistic work examining CDIs in mouse models uses animals obtained from a single source. We treated mice from 6 sources (2 University of Michigan colonies and 4 comm...

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Detalles Bibliográficos
Autores principales: Tomkovich, Sarah, Stough, Joshua M. A., Bishop, Lucas, Schloss, Patrick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7580958/
https://www.ncbi.nlm.nih.gov/pubmed/33087520
http://dx.doi.org/10.1128/mSphere.00869-20