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Automated Annotation of Sphingolipids Including Accurate Identification of Hydroxylation Sites Using MS(n) Data

[Image: see text] Sphingolipids constitute a heterogeneous lipid category that is involved in many key cellular functions. For high-throughput analyses of sphingolipids, tandem mass spectrometry (MS/MS) is the method of choice, offering sufficient sensitivity, structural information, and quantitativ...

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Detalles Bibliográficos
Autores principales: Hartler, Jürgen, Armando, Aaron M., Trötzmüller, Martin, Dennis, Edward A., Köfeler, Harald C., Quehenberger, Oswald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581017/
https://www.ncbi.nlm.nih.gov/pubmed/33003696
http://dx.doi.org/10.1021/acs.analchem.0c03016