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Identification of a cryptic submicroscopic deletion using a combination of fluorescence in situ hybridization and array comparative genomic hybridization in a t(3;5)(q25;q35)-positive acute myeloid leukemia patient: A case report and review of the literature

RATIONALE: The advent of high-resolution genome arrays including array comparative genomic hybridization (aCGH) has enabled the detection of cryptic submicroscopic deletions flanking translocation breakpoints in up to 20% of the apparently “balanced” structural chromosomal rearrangements in hematolo...

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Detalles Bibliográficos
Autores principales: Gao, Man, Li, Shibo, Wang, Lina, Nie, Shu, Pang, Hui, Lu, Xianglan, Wang, Xianfu, Wang, Mingwei, Guo, Shirong, Ma, Yuhan, Meng, Fanzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581054/
https://www.ncbi.nlm.nih.gov/pubmed/33120794
http://dx.doi.org/10.1097/MD.0000000000022789