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Donor-derived Cell-free DNA Combined With Histology Improves Prediction of Estimated Glomerular Filtration Rate Over Time in Kidney Transplant Recipients Compared With Histology Alone

Higher Banff inflammation and chronicity scores on kidney transplant biopsies are associated with poorer graft survival, although histology alone has limitations in predicting outcomes. We investigated if integrating donor-derived cell-free DNA (dd-cfDNA, Allosure; CareDx, Inc.) with Banff biopsy sc...

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Detalles Bibliográficos
Autores principales: Huang, Edmund, Gillespie, Matthew, Ammerman, Noriko, Vo, Ashley, Lim, Kathlyn, Peng, Alice, Najjar, Reiad, Sethi, Supreet, Jordan, Stanley C., Mirocha, James, Haas, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581058/
https://www.ncbi.nlm.nih.gov/pubmed/33134504
http://dx.doi.org/10.1097/TXD.0000000000001027