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DNA Methylation Age Is More Closely Associated With Infection Risk Than Chronological Age in Kidney Transplant Recipients

Older kidney transplant recipients demonstrate increased rates of infection but decreased rates of rejection compared with younger recipients, suggesting that older transplant patients are functionally overimmunosuppressed. We hypothesized that this is a consequence of reduction in immunological act...

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Detalles Bibliográficos
Autores principales: Schaenman, Joanna, Zhou, Xinkai, Guo, Rong, Rossetti, Maura, Liang, Emily C., Lum, Erik, Abdalla, Basmah, Bunnapradist, Suphamai, Pham, Phuong-Thu T., Danovitch, Gabriel, Karlamangla, Arun, Reed, Elaine, Horvath, Steve, Elashoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581059/
https://www.ncbi.nlm.nih.gov/pubmed/33134500
http://dx.doi.org/10.1097/TXD.0000000000001020