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Transient Destabilization of Biological Membranes Contributes to the Superior Performance of Star-Shaped PDMAEMA in Delivering pDNA

[Image: see text] Nonviral DNA vectors are promising alternatives to viral ones. Their use in DNA medicine is limited by an inability to transfect, for example, nondividing or suspension cells. In recent years, star-shaped synthetic polycationic vectors, so called “Nanostars”, have shown some promis...

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Detalles Bibliográficos
Autores principales: Jérôme, Valérie, Synatschke, Christopher V., Freitag, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581230/
https://www.ncbi.nlm.nih.gov/pubmed/33110991
http://dx.doi.org/10.1021/acsomega.0c03367