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Fast Purification of Recombinant Monomeric Amyloid-β from E. coli and Amyloid-β-mCherry Aggregates from Mammalian Cells
[Image: see text] The Alzheimer’s disease related peptide, Amyloid-beta (Aβ)1–40 and 1–42, has proven difficult to be purified as a recombinant monomeric protein due its expression in E. coli leading to the formation of insoluble inclusion bodies and its tendency to quickly form insoluble aggregates...
Autores principales: | Stephens, Amberley D., Lu, Meng, Fernandez-Villegas, Ana, Kaminski Schierle, Gabriele S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581289/ https://www.ncbi.nlm.nih.gov/pubmed/32960567 http://dx.doi.org/10.1021/acschemneuro.0c00300 |
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