Structural features and development of an assay platform of the parasite target deoxyhypusine synthase of Brugia malayi and Leishmania major

Deoxyhypusine synthase (DHS) catalyzes the first step of the post-translational modification of eukaryotic translation factor 5A (eIF5A), which is the only known protein containing the amino acid hypusine. Both proteins are essential for eukaryotic cell viability, and DHS has been suggested as a goo...

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Detalles Bibliográficos
Autores principales: Silva, Suélen Fernandes, Klippel, Angélica Hollunder, Ramos, Priscila Zonzini, Santiago, André da Silva, Valentini, Sandro Roberto, Bengtson, Mario Henrique, Massirer, Katlin Brauer, Bilsland, Elizabeth, Couñago, Rafael Miguez, Zanelli, Cleslei Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581365/
https://www.ncbi.nlm.nih.gov/pubmed/33044977
http://dx.doi.org/10.1371/journal.pntd.0008762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581365/
https://www.ncbi.nlm.nih.gov/pubmed/33044977
http://dx.doi.org/10.1371/journal.pntd.0008762

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