Precision installation of a highly efficient suicide gene safety switch in human induced pluripotent stem cells

Human pluripotent stem cells, including induced pluripotent stem cells (iPSCs) and embryonic stem cells, hold great promise for cell‐based therapies, but safety concerns that complicate consideration for routine clinical use remain. Installing a “safety switch” based on the inducible caspase‐9 (iCAS...

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Detalles Bibliográficos
Autores principales: Shi, Zhong‐Dong, Tchao, Jason, Wu, Ling, Carman, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581441/
https://www.ncbi.nlm.nih.gov/pubmed/32662231
http://dx.doi.org/10.1002/sctm.20-0007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581441/
https://www.ncbi.nlm.nih.gov/pubmed/32662231
http://dx.doi.org/10.1002/sctm.20-0007

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