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Precision installation of a highly efficient suicide gene safety switch in human induced pluripotent stem cells
Human pluripotent stem cells, including induced pluripotent stem cells (iPSCs) and embryonic stem cells, hold great promise for cell‐based therapies, but safety concerns that complicate consideration for routine clinical use remain. Installing a “safety switch” based on the inducible caspase‐9 (iCAS...
Autores principales: | Shi, Zhong‐Dong, Tchao, Jason, Wu, Ling, Carman, Aaron J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581441/ https://www.ncbi.nlm.nih.gov/pubmed/32662231 http://dx.doi.org/10.1002/sctm.20-0007 |
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