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Core transcriptional regulatory circuitries in cancer

Transcription factors (TFs) coordinate the on-and-off states of gene expression typically in a combinatorial fashion. Studies from embryonic stem cells and other cell types have revealed that a clique of self-regulated core TFs control cell identity and cell state. These core TFs form interconnected...

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Detalles Bibliográficos
Autores principales: Chen, Ye, Xu, Liang, Lin, Ruby Yu-Tong, Müschen, Markus, Koeffler, H. Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581508/
https://www.ncbi.nlm.nih.gov/pubmed/32943730
http://dx.doi.org/10.1038/s41388-020-01459-w