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IVIVC for Extended Release Hydrophilic Matrix Tablets in Consideration of Biorelevant Mechanical Stress

PURPOSE: When establishing IVIVC, a special problem arises by interpretation of averaged in vivo profiles insight of considerable individual variations in term of time and number of mechanical stress events in GI-tract. The objective of the study was to investigate and forecast the effect of mechani...

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Detalles Bibliográficos
Autores principales: Mohylyuk, Valentyn, Goldoozian, Seyedreza, Andrews, Gavin P., Dashevskiy, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581586/
https://www.ncbi.nlm.nih.gov/pubmed/33094368
http://dx.doi.org/10.1007/s11095-020-02940-7