Adenosine and ATPγS protect against bacterial pneumonia-induced acute lung injury

Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, disrupts the alveolar-capillary barrier, triggering pulmonary vascular leak thus inducing acute lung injury (ALI). Extracellular purines, adenosine and ATP, protected against ALI induced by purified LPS. In this s...

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Detalles Bibliográficos
Autores principales: Gross, Christine M., Kovacs-Kasa, Anita, Meadows, Mary Louise, Cherian-Shaw, Mary, Fulton, David J., Verin, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581771/
https://www.ncbi.nlm.nih.gov/pubmed/33093565
http://dx.doi.org/10.1038/s41598-020-75224-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581771/
https://www.ncbi.nlm.nih.gov/pubmed/33093565
http://dx.doi.org/10.1038/s41598-020-75224-0

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