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SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production

The inhibitory immunoreceptor SIRPα is expressed on myeloid and neuronal cells and interacts with the broadly expressed CD47. CD47-SIRPα interactions form an innate immune checkpoint and its targeting has shown promising results in cancer patients. Here, we report expression of SIRPα on B1 lymphocyt...

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Detalles Bibliográficos
Autores principales: Franke, Katka, Pillai, Saravanan Y., Hoogenboezem, Mark, Gijbels, Marion J. J., Matlung, Hanke L., Geissler, Judy, Olsman, Hugo, Pottgens, Chantal, van Gorp, Patrick J., Ozsvar-Kozma, Maria, Saito, Yasuyuki, Matozaki, Takashi, Kuijpers, Taco W., Hendriks, Rudi W., Kraal, Georg, Binder, Christoph J., de Winther, Menno P. J., van den Berg, Timo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581795/
https://www.ncbi.nlm.nih.gov/pubmed/33162986
http://dx.doi.org/10.3389/fimmu.2020.570963