Cargando…
SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production
The inhibitory immunoreceptor SIRPα is expressed on myeloid and neuronal cells and interacts with the broadly expressed CD47. CD47-SIRPα interactions form an innate immune checkpoint and its targeting has shown promising results in cancer patients. Here, we report expression of SIRPα on B1 lymphocyt...
Autores principales: | Franke, Katka, Pillai, Saravanan Y., Hoogenboezem, Mark, Gijbels, Marion J. J., Matlung, Hanke L., Geissler, Judy, Olsman, Hugo, Pottgens, Chantal, van Gorp, Patrick J., Ozsvar-Kozma, Maria, Saito, Yasuyuki, Matozaki, Takashi, Kuijpers, Taco W., Hendriks, Rudi W., Kraal, Georg, Binder, Christoph J., de Winther, Menno P. J., van den Berg, Timo K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581795/ https://www.ncbi.nlm.nih.gov/pubmed/33162986 http://dx.doi.org/10.3389/fimmu.2020.570963 |
Ejemplares similares
-
CD47-SIRPα Checkpoint Inhibition Enhances Neutrophil-Mediated Killing of Dinutuximab-Opsonized Neuroblastoma Cells
por: Martínez-Sanz, Paula, et al.
Publicado: (2021) -
Immunoreceptors on neutrophils
por: van Rees, Dieke J., et al.
Publicado: (2016) -
BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells
por: van Helden, Mary J, et al.
Publicado: (2023) -
Absence of p55 TNF Receptor Reduces Atherosclerosis, but Has No Major Effect on Angiotensin II Induced Aneurysms in LDL Receptor Deficient Mice
por: Xanthoulea, Sofia, et al.
Publicado: (2009) -
Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing
por: van Rees, Dieke J., et al.
Publicado: (2022)