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TIMELESS regulates sphingolipid metabolism and tumor cell growth through Sp1/ACER2/S1P axis in ER-positive breast cancer

Breast cancer is one of the most common female malignant cancers. Biorhythm disorder largely increases the risk of breast cancer. We aimed to investigate the biological functions and molecular mechanisms of circadian gene TIMELESS circadian regulator (TIM) in estrogen receptor (ER)-positive breast c...

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Detalles Bibliográficos
Autores principales: Zhang, Shan, Huang, Peiqi, Dai, Huijuan, Li, Qing, Hu, Lipeng, Peng, Jing, Jiang, Shuheng, Xu, Yaqian, Wu, Ziping, Nie, Huizhen, Zhang, Zhigang, Yin, Wenjin, Zhang, Xueli, Lu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581802/
https://www.ncbi.nlm.nih.gov/pubmed/33093451
http://dx.doi.org/10.1038/s41419-020-03106-4