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Transport of ultrasmall gold nanoparticles (2 nm) across the blood–brain barrier in a six-cell brain spheroid model

The blood–brain barrier (BBB) is an efficient barrier for molecules and drugs. Multicellular 3D spheroids display reproducible BBB features and functions. The spheroids used here were composed of six brain cell types: Astrocytes, pericytes, endothelial cells, microglia cells, oligodendrocytes, and n...

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Detalles Bibliográficos
Autores principales: Sokolova, Viktoriya, Mekky, Gehad, van der Meer, Selina Beatrice, Seeds, Michael C., Atala, Anthony J., Epple, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581805/
https://www.ncbi.nlm.nih.gov/pubmed/33093563
http://dx.doi.org/10.1038/s41598-020-75125-2