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Transport of ultrasmall gold nanoparticles (2 nm) across the blood–brain barrier in a six-cell brain spheroid model
The blood–brain barrier (BBB) is an efficient barrier for molecules and drugs. Multicellular 3D spheroids display reproducible BBB features and functions. The spheroids used here were composed of six brain cell types: Astrocytes, pericytes, endothelial cells, microglia cells, oligodendrocytes, and n...
Autores principales: | Sokolova, Viktoriya, Mekky, Gehad, van der Meer, Selina Beatrice, Seeds, Michael C., Atala, Anthony J., Epple, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581805/ https://www.ncbi.nlm.nih.gov/pubmed/33093563 http://dx.doi.org/10.1038/s41598-020-75125-2 |
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