Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency

Third-generation HIV-1-derived lentiviral vectors are successfully used as therapeutic agents in various clinical applications. To further promote their use, we attempted to enhance vector infectivity by targeting the dimerization and packaging properties of the RNA transfer vector based on the prem...

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Detalles Bibliográficos
Autores principales: Vamva, Eirini, Lever, Andrew M.L., Vink, Conrad A., Kenyon, Julia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581820/
https://www.ncbi.nlm.nih.gov/pubmed/33145367
http://dx.doi.org/10.1016/j.omtm.2020.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581820/
https://www.ncbi.nlm.nih.gov/pubmed/33145367
http://dx.doi.org/10.1016/j.omtm.2020.09.010

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