Preparation of parenteral nanocrystal suspensions of etoposide from the excipient free dry state of the drug to enhance in vivo antitumoral properties

Nanoparticle technology in cancer chemotherapy is a promising approach to enhance active ingredient pharmacology and pharmacodynamics. Indeed, drug nanoparticles display various assets such as extended blood lifespan, high drug loading and reduced cytotoxicity leading to better drug compliance. In t...

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Detalles Bibliográficos
Autores principales: Martin, Brice, Seguin, Johanne, Annereau, Maxime, Fleury, Thomas, Lai-Kuen, René, Neri, Giovanni, Lam, Anita, Bally, Marcel, Mignet, Nathalie, Corvis, Yohann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581827/
https://www.ncbi.nlm.nih.gov/pubmed/33093456
http://dx.doi.org/10.1038/s41598-020-74809-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581827/
https://www.ncbi.nlm.nih.gov/pubmed/33093456
http://dx.doi.org/10.1038/s41598-020-74809-z

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