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Three-Dimensional Models as a New Frontier for Studying the Role of Proteoglycans in the Normal and Malignant Breast Microenvironment

The extracellular matrix (ECM) provides cues to direct mammogenesis, tumourigenesis and metastatic processes. Over the past several decades, two-dimensional (2D) culture models have been invaluable in furthering our understanding of the tumor microenvironment (TME), however, they still do not accura...

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Detalles Bibliográficos
Autores principales: Clegg, Julien, Koch, Maria K., Thompson, Erik W., Haupt, Larisa M., Kalita-de Croft, Priyakshi, Bray, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581852/
https://www.ncbi.nlm.nih.gov/pubmed/33163489
http://dx.doi.org/10.3389/fcell.2020.569454