Differential DNA methylation in familial hypercholesterolemia

BACKGROUND: Familial hypercholesterolemia (FH) is a monogenic disorder characterized by elevated low-density lipoprotein cholesterol (LDL-C). A FH causing genetic variant in LDLR, APOB, or PCSK9 is not identified in 12–60% of clinical FH patients (FH mutation-negative patients). We aimed to assess w...

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Detalles Bibliográficos
Autores principales: Reeskamp, Laurens F., Venema, Andrea, Pereira, Joao P.Belo, Levin, Evgeni, Nieuwdorp, Max, Groen, Albert K., Defesche, Joep C., Grefhorst, Aldo, Henneman, Peter, Hovingh, G.Kees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581877/
https://www.ncbi.nlm.nih.gov/pubmed/33096472
http://dx.doi.org/10.1016/j.ebiom.2020.103079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581877/
https://www.ncbi.nlm.nih.gov/pubmed/33096472
http://dx.doi.org/10.1016/j.ebiom.2020.103079

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