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Histone Deacetylase Inhibition in Non-small Cell Lung Cancer: Hype or Hope?
Epigenetic modulation, including acetylation, methylation, phosphorylation, and ubiquitination, plays a pivotal role in regulation of gene expression. Histone acetylation—a balance between the activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs)—is one of the key epigenet...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581936/ https://www.ncbi.nlm.nih.gov/pubmed/33163495 http://dx.doi.org/10.3389/fcell.2020.582370 |