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APPL1 negatively regulates bone mass, possibly by controlling the fate of bone marrow mesenchymal progenitor cells

Adiponectin is an adipokine that can exert a regulatory function on bone metabolism. However, there are many contradictions between clinical and pre-clinical studies on adiponectin. APPL1 is an adaptor protein that can interact with adiponectin receptors. In the current study, we found that knockout...

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Detalles Bibliográficos
Autores principales: LIN, Yuan-Yu, DONG, Lily Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581959/
https://www.ncbi.nlm.nih.gov/pubmed/33041270
http://dx.doi.org/10.2183/pjab.96.027