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APPL1 negatively regulates bone mass, possibly by controlling the fate of bone marrow mesenchymal progenitor cells
Adiponectin is an adipokine that can exert a regulatory function on bone metabolism. However, there are many contradictions between clinical and pre-clinical studies on adiponectin. APPL1 is an adaptor protein that can interact with adiponectin receptors. In the current study, we found that knockout...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Academy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581959/ https://www.ncbi.nlm.nih.gov/pubmed/33041270 http://dx.doi.org/10.2183/pjab.96.027 |