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Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

Metabolic reprogramming is associated with re/activation and antagonism of androgen receptor (AR) signaling that drives prostate cancer (PCa) progression to castration resistance, respectively. In particular, AR signaling influences the fates of citrate that uniquely characterizes normal and maligna...

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Detalles Bibliográficos
Autores principales: Uo, Takuma, Sprenger, Cynthia C., Plymate, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581990/
https://www.ncbi.nlm.nih.gov/pubmed/33163409
http://dx.doi.org/10.3389/fonc.2020.580617