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Breast cancer cell debris diminishes therapeutic efficacy through heme oxygenase-1-mediated inactivation of M1-like tumor-associated macrophages

Chemotherapy is commonly used as a major therapeutic option for breast cancer treatment, but its efficacy is often diminished by disruption of patient’s anti-tumor immunity. Chemotherapy-generated tumor cell debris could hijack accumulated tumor-associated macrophages (TAMs), provoking tumor recurre...

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Detalles Bibliográficos
Autores principales: Kim, Seung Hyeon, Saeidi, Soma, Zhong, Xiancai, Gwak, Shin-Young, Muna, Ishrat Aklima, Park, Sin-Aye, Kim, Seong Hoon, Na, Hye-Kyung, Joe, Yeonsoo, Chung, Hun Taeg, Kim, Kyoung-Eun, Han, Wonshik, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581991/
https://www.ncbi.nlm.nih.gov/pubmed/33039895
http://dx.doi.org/10.1016/j.neo.2020.08.006