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Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids

Gene therapy is being investigated for a range of serious lung diseases, such as cystic fibrosis and emphysema. Recombinant adeno-associated virus (rAAV) is a well-established, safe, viral vector for gene delivery with multiple naturally occurring and artificial serotypes available displaying altern...

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Detalles Bibliográficos
Autores principales: Meyer-Berg, Helena, Zhou Yang, Lucia, Pilar de Lucas, María, Zambrano, Alberto, Hyde, Stephen C., Gill, Deborah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582027/
https://www.ncbi.nlm.nih.gov/pubmed/33097094
http://dx.doi.org/10.1186/s13287-020-01950-x