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Identification of AAV serotypes for lung gene therapy in human embryonic stem cell-derived lung organoids
Gene therapy is being investigated for a range of serious lung diseases, such as cystic fibrosis and emphysema. Recombinant adeno-associated virus (rAAV) is a well-established, safe, viral vector for gene delivery with multiple naturally occurring and artificial serotypes available displaying altern...
Autores principales: | Meyer-Berg, Helena, Zhou Yang, Lucia, Pilar de Lucas, María, Zambrano, Alberto, Hyde, Stephen C., Gill, Deborah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582027/ https://www.ncbi.nlm.nih.gov/pubmed/33097094 http://dx.doi.org/10.1186/s13287-020-01950-x |
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