Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network

The maintenance of genomic stability relies on DNA damage sensor kinases that detect DNA lesions and phosphorylate an extensive network of substrates. The Mec1/ATR kinase is one of the primary sensor kinases responsible for orchestrating DNA damage responses. Despite the importance of Mec1/ATR, the...

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Detalles Bibliográficos
Autores principales: Faca, Vitor Marcel, Sanford, Ethan J., Tieu, Jennifer, Comstock, William, Gupta, Shagun, Marshall, Shannon, Yu, Haiyuan, Smolka, Marcus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582137/
https://www.ncbi.nlm.nih.gov/pubmed/33093574
http://dx.doi.org/10.1038/s41598-020-74939-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582137/
https://www.ncbi.nlm.nih.gov/pubmed/33093574
http://dx.doi.org/10.1038/s41598-020-74939-4

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