miR-322/-503 rescues myoblast defects in myotonic dystrophy type 1 cell model by targeting CUG repeats

Myotonic dystrophy type 1 (DM1) is the most common type of adult muscular dystrophy caused by the expanded triple-nucleotides (CUG) repeats. Myoblast in DM1 displayed many defects, including defective myoblast differentiation, ribonuclear foci, and aberrant alternative splicing. Despite many were re...

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Detalles Bibliográficos
Autores principales: Shen, Xiaopeng, Xu, Feng, Li, Meng, Wu, Shen, Zhang, Jingyi, Wang, Ao, Xu, Lei, Liu, Yu, Zhu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582138/
https://www.ncbi.nlm.nih.gov/pubmed/33093470
http://dx.doi.org/10.1038/s41419-020-03112-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582138/
https://www.ncbi.nlm.nih.gov/pubmed/33093470
http://dx.doi.org/10.1038/s41419-020-03112-6

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