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BET degrader inhibits tumor progression and stem-like cell growth via Wnt/β-catenin signaling repression in glioma cells
Based on their histological appearance, gliomas are a very common primary tumor type of the brain and are classified into grades, Grade I to Grade IV, of the World Health Organization. Treatment failure is due to the cancer stem cells (CSC) phenotype maintenance and self-renewal. BET degraders such...
| Autores principales: | , , , , |
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| 格式: | Online 文件 Texto |
| 语言: | English |
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Nature Publishing Group UK
2020
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| 主题: | |
| 在线阅读: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582157/ https://www.ncbi.nlm.nih.gov/pubmed/33093476 http://dx.doi.org/10.1038/s41419-020-03117-1 |