Cargando…

BET degrader inhibits tumor progression and stem-like cell growth via Wnt/β-catenin signaling repression in glioma cells

Based on their histological appearance, gliomas are a very common primary tumor type of the brain and are classified into grades, Grade I to Grade IV, of the World Health Organization. Treatment failure is due to the cancer stem cells (CSC) phenotype maintenance and self-renewal. BET degraders such...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Tao, Guo, Tongqi, Zhen, Wei, Zou, Jianjun, Li, Fuyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582157/ https://www.ncbi.nlm.nih.gov/pubmed/33093476 http://dx.doi.org/10.1038/s41419-020-03117-1

Ejemplares similares

Human neural stem cells repress glioma cell progression in a paracrine manner by downregulating the Wnt/β‐catenin signalling pathway
por: Yin, Xiaolin, et al.
Publicado: (2023)

Zeylenone represses the progress of human prostate cancer by downregulating the Wnt/β-catenin pathway
por: Zeng, Shaohua, et al.
Publicado: (2018)

Repression of Wnt/β-catenin signaling by SOX9 and Mastermind-like transcriptional coactivator 2
por: Sinha, Abhishek, et al.
Publicado: (2021)

Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling
por: Lin, Chung-Ming, et al.
Publicado: (2017)

SETDB1 promotes glioblastoma growth via CSF-1-dependent macrophage recruitment by activating the AKT/mTOR signaling pathway
por: Han, Shuai, et al.
Publicado: (2020)

Retraction Note: SETDB1 promotes glioblastoma growth via CSF-1-dependent macrophage recruitment by activating the AKT/mTOR signaling pathway
por: Han, Shuai, et al.
Publicado: (2022)

TROAP regulates cell cycle and promotes tumor progression through Wnt/β‐Catenin signaling pathway in glioma cells
por: Zhao, Zong‐qing, et al.
Publicado: (2021)

Protein Kinase PKN1 Represses Wnt/β-Catenin Signaling in Human Melanoma Cells
por: James, Richard G., et al.
Publicado: (2013)

Repression of Wnt/β-catenin response elements by p63 (TP63)
por: Katoh, Iyoko, et al.
Publicado: (2016)

α-Catenin interacts with APC to regulate β-catenin proteolysis and transcriptional repression of Wnt target genes
por: Choi, Seung H., et al.
Publicado: (2013)

Tunicamycin inhibits progression of glioma cells through downregulation of the MEG-3-regulated wnt/β-catenin signaling pathway
por: Li, Xin, et al.
Publicado: (2018)

Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway
por: Jeong, Woo-Jeong, et al.
Publicado: (2018)

Lysophosphatidic acid enhances neointimal hyperplasia following vascular injury through modulating proliferation, autophagy, inflammation and oxidative stress
por: Shen, Xuhui, et al.
Publicado: (2018)

RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma
por: Cao, Yingyue, et al.
Publicado: (2022)

Presenilin1 exerts antiproliferative effects by repressing the Wnt/β-catenin pathway in glioblastoma
por: Yang, Wei, et al.
Publicado: (2020)

Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma
por: Yu, Jiarui, et al.
Publicado: (2021)

miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling
por: Li, San-Zhong, et al.
Publicado: (2021)

Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin
por: Xiao, Jialing, et al.
Publicado: (2022)

Deubiquitination of TNKS1 Regulates Wnt/β-Catenin to Affect the Expression of USP25 to Promote the Progression of Glioma
por: Tang, Bin, et al.
Publicado: (2022)

MAGI3 negatively regulates Wnt/β-catenin signaling and suppresses malignant phenotypes of glioma cells
por: Ma, Qian, et al.
Publicado: (2015)

TIPE2 Inhibits Hypoxia-Induced Wnt/β-Catenin Pathway Activation and EMT in Glioma Cells
por: Liu, Zhi-jun, et al.
Publicado: (2016)

Downregulation of TET1 Promotes Glioma Cell Proliferation and Invasion by Targeting Wnt/β-Catenin Pathway
por: Ji, Jianwen, et al.
Publicado: (2021)

Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/β-Catenin-Dependent and Wnt/β-Catenin-Independent Signaling Networks in the Human Liver Cancer
por: Chen, Jiayu, et al.
Publicado: (2020)

Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation
por: Kim, Wantae, et al.
Publicado: (2017)

Foxf2 represses bone formation via Wnt2b/β-catenin signaling
por: Tanaka, Tomoyuki, et al.
Publicado: (2022)

Tcf3 Represses Wnt–β-Catenin Signaling and Maintains Neural Stem Cell Population during Neocortical Development
por: Kuwahara, Atsushi, et al.
Publicado: (2014)

Salinomycin repressed the epithelial–mesenchymal transition of epithelial ovarian cancer cells via downregulating Wnt/β-catenin pathway
por: Li, Rui, et al.
Publicado: (2017)

BMI1 promotes spermatogonial stem cell maintenance by epigenetically repressing Wnt10b/β-catenin signaling
por: Yu, Jun, et al.
Publicado: (2022)

The Role of Fluoxetine in Activating Wnt/β-Catenin Signaling and Repressing β-Amyloid Production in an Alzheimer Mouse Model
por: Huang, Min, et al.
Publicado: (2018)

WNT/β-Catenin-Mediated Resistance to Glucose Deprivation in Glioblastoma Stem-like Cells
por: Yusuf, Suad, et al.
Publicado: (2022)

Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling
por: Miyamoto, Kentaro, et al.
Publicado: (2017)

MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma
por: Wang, Qiong, et al.
Publicado: (2018)

MicroRNA-301a/ZNRF3/wnt/β-catenin signal regulatory crosstalk mediates glioma progression
por: Sun, Jikui, et al.
Publicado: (2020)

Cell intrinsic Wnt/β-catenin signaling activation
por: Bernkopf, Dominic B., et al.
Publicado: (2018)

Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
por: MIAO, JUNJIE, et al.
Publicado: (2015)

PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β-catenin signaling pathway
por: Ma, Dede, et al.
Publicado: (2020)

Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling
por: Tao, Bei, et al.
Publicado: (2021)

NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation
por: Wang, Q, et al.
Publicado: (2013)

miR-140-3p enhances cisplatin sensitivity and attenuates stem cell-like properties through repressing Wnt/β-catenin signaling in lung adenocarcinoma cells
por: Wu, Shuoming, et al.
Publicado: (2020)

Corilagin Represses Epithelial to Mesenchymal Transition Process Through Modulating Wnt/β-Catenin Signaling Cascade
por: Hwang, Sun Tae, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4gtn4aul34c7ts9bspcg89b00o