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BET degrader inhibits tumor progression and stem-like cell growth via Wnt/β-catenin signaling repression in glioma cells

Based on their histological appearance, gliomas are a very common primary tumor type of the brain and are classified into grades, Grade I to Grade IV, of the World Health Organization. Treatment failure is due to the cancer stem cells (CSC) phenotype maintenance and self-renewal. BET degraders such...

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Bibliografische gegevens
Hoofdauteurs: Tian, Tao, Guo, Tongqi, Zhen, Wei, Zou, Jianjun, Li, Fuyong
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582157/
https://www.ncbi.nlm.nih.gov/pubmed/33093476
http://dx.doi.org/10.1038/s41419-020-03117-1