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Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum

Major depressive disorder (MDD) is a complex condition with unclear pathophysiology. Molecular disruptions within limbic brain regions and the periphery contribute to depression symptomatology and a more complete understanding the diversity of molecular changes that occur in these tissues may guide...

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Detalles Bibliográficos
Autores principales: Hamilton, Peter J., Chen, Emily Y., Tolstikov, Vladimir, Peña, Catherine J., Picone, Joseph A., Shah, Punit, Panagopoulos, Kiki, Strat, Ana N., Walker, Deena M., Lorsch, Zachary S., Robinson, Hannah L., Mervosh, Nicholas L., Kiraly, Drew D., Sarangarajan, Rangaprasad, Narain, Niven R., Kiebish, Michael A., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582177/
https://www.ncbi.nlm.nih.gov/pubmed/33093530
http://dx.doi.org/10.1038/s41598-020-75114-5