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Epigenetic alterations in skin homing CD4(+)CLA(+) T cells of atopic dermatitis patients

T cells expressing the cutaneous lymphocyte antigen (CLA) mediate pathogenic inflammation in atopic dermatitis (AD). The molecular alterations contributing to their dysregulation remain unclear. With the aim to elucidate putative altered pathways in AD we profiled DNA methylation levels and miRNA ex...

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Detalles Bibliográficos
Autores principales: Acevedo, Nathalie, Benfeitas, Rui, Katayama, Shintaro, Bruhn, Sören, Andersson, Anna, Wikberg, Gustav, Lundeberg, Lena, Lindvall, Jessica M., Greco, Dario, Kere, Juha, Söderhäll, Cilla, Scheynius, Annika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582180/
https://www.ncbi.nlm.nih.gov/pubmed/33093567
http://dx.doi.org/10.1038/s41598-020-74798-z