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Epigenetic alterations in skin homing CD4(+)CLA(+) T cells of atopic dermatitis patients
T cells expressing the cutaneous lymphocyte antigen (CLA) mediate pathogenic inflammation in atopic dermatitis (AD). The molecular alterations contributing to their dysregulation remain unclear. With the aim to elucidate putative altered pathways in AD we profiled DNA methylation levels and miRNA ex...
Autores principales: | Acevedo, Nathalie, Benfeitas, Rui, Katayama, Shintaro, Bruhn, Sören, Andersson, Anna, Wikberg, Gustav, Lundeberg, Lena, Lindvall, Jessica M., Greco, Dario, Kere, Juha, Söderhäll, Cilla, Scheynius, Annika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582180/ https://www.ncbi.nlm.nih.gov/pubmed/33093567 http://dx.doi.org/10.1038/s41598-020-74798-z |
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