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Carbapenems drive the collateral resistance to ceftaroline in cystic fibrosis patients with MRSA

Chronic airways infection with methicillin-resistant Staphylococcus aureus (MRSA) is associated with worse respiratory disease cystic fibrosis (CF) patients. Ceftaroline is a cephalosporin that inhibits the penicillin-binding protein (PBP2a) uniquely produced by MRSA. We analyzed 335 S. aureus isola...

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Detalles Bibliográficos
Autores principales: Varela, Maria Celeste, Roch, Melanie, Taglialegna, Agustina, Long, Scott W., Saavedra, Matthew Ojeda, Rose, Warren E., Davis, James J., Hoffman, Lucas R., Hernandez, Rafael E., Rosato, Roberto R., Rosato, Adriana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582194/
https://www.ncbi.nlm.nih.gov/pubmed/33093601
http://dx.doi.org/10.1038/s42003-020-01313-5