Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening

The screening of chemical libraries based on cellular biosensors is a useful approach to identify new hits for novel therapeutic targets involved in rare genetic pathologies, such as β-thalassemia and sickle cell disease. In particular, pharmacologically mediated stimulation of human γ-globin gene e...

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Detalles Bibliográficos
Autores principales: Breveglieri, Giulia, Pacifico, Salvatore, Zuccato, Cristina, Cosenza, Lucia Carmela, Sultan, Shaiq, D’Aversa, Elisabetta, Gambari, Roberto, Preti, Delia, Trapella, Claudio, Guerrini, Remo, Borgatti, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582302/
https://www.ncbi.nlm.nih.gov/pubmed/33050052
http://dx.doi.org/10.3390/ijms21197426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582302/
https://www.ncbi.nlm.nih.gov/pubmed/33050052
http://dx.doi.org/10.3390/ijms21197426

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