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Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke

The motor protein myosin drives a wide range of cellular and muscular functions by generating directed movement and force, fueled through adenosine triphosphate (ATP) hydrolysis. Release of the hydrolysis product adenosine diphosphate (ADP) is a fundamental and regulatory process during force produc...

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Detalles Bibliográficos
Autores principales: Ewert, Wiebke, Franz, Peter, Tsiavaliaris, Georgios, Preller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582316/
https://www.ncbi.nlm.nih.gov/pubmed/33049993
http://dx.doi.org/10.3390/ijms21197417