Involvement of Mitochondrial Mechanisms in the Cytostatic Effect of Desethylamiodarone in B16F10 Melanoma Cells

Previously, we showed that desethylamiodarone (DEA), a major metabolite of the widely used antiarrhythmic drug amiodarone, has direct mitochondrial effects. We hypothesized that these effects account for its observed cytotoxic properties and ability to limit in vivo metastasis. Accordingly, we exami...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramadan, Fadi H. J., Szabo, Aliz, Kovacs, Dominika, Takatsy, Aniko, Bognar, Rita, Gallyas, Ferenc, Bognar, Zita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582344/
https://www.ncbi.nlm.nih.gov/pubmed/33027919
http://dx.doi.org/10.3390/ijms21197346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582344/
https://www.ncbi.nlm.nih.gov/pubmed/33027919
http://dx.doi.org/10.3390/ijms21197346

Ejemplares similares