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Patient-Derived Induced Pluripotent Stem Cell-Based Models in Parkinson’s Disease for Drug Identification

Parkinson’s disease (PD) is a common progressive neurodegenerative disorder characterized by loss of striatal-projecting dopaminergic neurons of the ventral forebrain, resulting in motor and cognitive deficits. Despite extensive efforts in understanding PD pathogenesis, no disease-modifying drugs ex...

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Detalles Bibliográficos
Autores principales: Kouroupi, Georgia, Antoniou, Nasia, Prodromidou, Kanella, Taoufik, Era, Matsas, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582359/
https://www.ncbi.nlm.nih.gov/pubmed/32993172
http://dx.doi.org/10.3390/ijms21197113