Cargando…

Bis-Lactam Peptide [i, i+4]-Stapling with α-Methylated Thialysines

Four bis-lactam [i, i+4]-stapled peptides with d- or l-α-methyl-thialysines were constructed on a model peptide sequence derived from p110α[E545K] and subjected to circular dichroism (CD) and proteolytic stability assessment, alongside the corresponding bis-lactam [i, i+4]-stapled peptide with l-thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Bo, Zheng, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582373/
https://www.ncbi.nlm.nih.gov/pubmed/33019638
http://dx.doi.org/10.3390/molecules25194506