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T Cell Activation Machinery: Form and Function in Natural and Engineered Immune Receptors

The impressive success of chimeric antigen receptor (CAR)-T cell therapies in treating advanced B-cell malignancies has spurred a frenzy of activity aimed at developing CAR-T therapies for other cancers, particularly solid tumors, and optimizing engineered T cells for maximum clinical benefit in man...

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Detalles Bibliográficos
Autores principales: Chandler, Nicholas J., Call, Melissa J., Call, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582382/
https://www.ncbi.nlm.nih.gov/pubmed/33050044
http://dx.doi.org/10.3390/ijms21197424