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T Cell Activation Machinery: Form and Function in Natural and Engineered Immune Receptors

The impressive success of chimeric antigen receptor (CAR)-T cell therapies in treating advanced B-cell malignancies has spurred a frenzy of activity aimed at developing CAR-T therapies for other cancers, particularly solid tumors, and optimizing engineered T cells for maximum clinical benefit in man...

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Detalles Bibliográficos
Autores principales:	Chandler, Nicholas J., Call, Melissa J., Call, Matthew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582382/ https://www.ncbi.nlm.nih.gov/pubmed/33050044 http://dx.doi.org/10.3390/ijms21197424

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