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Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine

Tumorigenesis is a multiphasic process in which genetic alterations guide the progressive transformation in cancer cells1. In order to evaluate the possible correlation between some gene variants and the risk of the toxicity development onset, two of the polymorphisms of the thymidylate synthase (TY...

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Detalles Bibliográficos
Autores principales: Vitello, Stefano, Di Liegro, Italia, Ricciardi, Maria Rita, Verga, Chiara, Amato, Alessandra, Schiera, Gabriella, Di Liegro, Carlo, Messina, Giuseppe, Proia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582406/
https://www.ncbi.nlm.nih.gov/pubmed/33117504
http://dx.doi.org/10.4081/ejtm.2020.8970