Sex Does Not Influence Visual Outcomes After Blast-Mediated Traumatic Brain Injury but IL-1 Pathway Mutations Confer Partial Rescue

PURPOSE: In a mouse model of blast-mediated traumatic brain injury (bTBI), interleukin-1 (IL-1)-pathway components were tested as potential therapeutic targets for bTBI-mediated retinal ganglion cell (RGC) dysfunction. Sex was also evaluated as a variable for RGC outcomes post-bTBI. METHODS: Male an...

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Detalles Bibliográficos
Autores principales: Evans, Lucy P., Boehme, Nickolas, Wu, Shu, Burghardt, Elliot L., Akurathi, Abhigna, Todd, Brittany P., Newell, Elizabeth A., Ferguson, Polly J., Mahajan, Vinit B., Dutca, Laura M., Harper, Matthew M., Bassuk, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582458/
https://www.ncbi.nlm.nih.gov/pubmed/33030508
http://dx.doi.org/10.1167/iovs.61.12.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582458/
https://www.ncbi.nlm.nih.gov/pubmed/33030508
http://dx.doi.org/10.1167/iovs.61.12.7

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