Antioxidant Amelioration of Riboflavin Transporter Deficiency in Motoneurons Derived from Patient-Specific Induced Pluripotent Stem Cells

Mitochondrial dysfunction is a key element in the pathogenesis of neurodegenerative disorders, such as riboflavin transporter deficiency (RTD). This is a rare, childhood-onset disease characterized by motoneuron degeneration and caused by mutations in SLC52A2 and SLC52A3, encoding riboflavin (RF) tr...

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Detalles Bibliográficos
Autores principales: Marioli, Chiara, Magliocca, Valentina, Petrini, Stefania, Niceforo, Alessia, Borghi, Rossella, Petrillo, Sara, La Rosa, Piergiorgio, Colasuonno, Fiorella, Persichini, Tiziana, Piemonte, Fiorella, Massey, Keith, Tartaglia, Marco, Moreno, Sandra, Bertini, Enrico, Compagnucci, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582490/
https://www.ncbi.nlm.nih.gov/pubmed/33036493
http://dx.doi.org/10.3390/ijms21197402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582490/
https://www.ncbi.nlm.nih.gov/pubmed/33036493
http://dx.doi.org/10.3390/ijms21197402

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