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Cytotoxic and Senolytic Effects of Methadone in Combination with Temozolomide in Glioblastoma Cells

Methadone is an analgesic drug used for pain treatment and heroin substitution. Recently, methadone has been proposed to be useful also for cancer therapy, including glioblastoma multiforme (GBM), the most severe form of brain cancer, because experiments on cultured glioma cells treated with doxorub...

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Detalles Bibliográficos
Autores principales: Kaina, Bernd, Beltzig, Lea, Piee-Staffa, Andrea, Haas, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582495/
https://www.ncbi.nlm.nih.gov/pubmed/32977591
http://dx.doi.org/10.3390/ijms21197006