The Roles of SPOP in DNA Damage Response and DNA Replication

Speckle-type BTB/POZ protein (SPOP) is a substrate recognition receptor of the cullin-3 (CUL3)/RING type ubiquitin E3 complex. To date, approximately 30 proteins have been identified as ubiquitinated substrates of the CUL3/SPOP complex. Pathologically, missense mutations in the substrate-binding dom...

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Detalles Bibliográficos
Autores principales: Maekawa, Masashi, Higashiyama, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582541/
https://www.ncbi.nlm.nih.gov/pubmed/33023230
http://dx.doi.org/10.3390/ijms21197293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582541/
https://www.ncbi.nlm.nih.gov/pubmed/33023230
http://dx.doi.org/10.3390/ijms21197293

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